Special Organic Chemistry Lab I
CHM 245 - Spring 2008
Friday 11:30 am- 3:00 pm, AA429C

Instructor: Zikiya Norton, Ph.D.
Email: znorton@nvcc.edu
Phone: 703-845-4627
Office Hours (AA352): M 1:00-3:00,  R 1:00-3:00

TEXT
1) Experimental Organic Chemistry: A Miniscale and Microscale Approach Gilbert & Martin, 4th edition
(This is on reserve in the library)

2) CHM 245/246 “Lab Manual”

The Lab Manual gives experimental details as to how we will be doing the experiment. The Gilbert book will give you context and theory for the experiments you perform. You are expected to read the first three chapters of the Gilbert before Melting points lab; you will continue reading in advance.  We will not be doing any "microscale" techniques.
 

OTHER REQUIRED MATERIALS
1) Splash-proof laboratory goggles – these can be purchased from the bookstore
2) Bound laboratory notebook – no spiral bound, no loose leaf, you need a marble notebook or something similar.
Link to notebook guidelines
3) Proper attire – feet must be completely covered, no sandals, no crocs, you should also be covered from shoulders to knees.
Link to all safety procedures

 
TENTATIVE LAB SCHEDULE
Date Lab Activity Lab Manual Online Guides Reading Assignment Prelab
1/30 Safety and Introduction   Lab Tour Ch 1 & 2 (all)  
2/6 Melting Point of an Unknown MP Lab MP Instrument Guide Ch 3.3 MP Prelab
2/13 Recrystallization of Benzoic Acid RC Lab RC Intro Ch 3.1, 3.2 RC Prelab
2/20 Simple Distillation of Salt Water SD Lab SD Intro Ch 4.1, 4.2, 4.3 SD Prelab
2/27 Fractional Distillation FD Lab FD Intro
 		 Ch 4.4 FD Prelab
3/5 Index of Refraction   Refractive Index Guide    
3/12 Spring Break, No Lab        
3/19 Gas Chromatography GC Lab GC Intro Ch 6.4 GC Prelab
3/26 Acid/Base Extraction EX Lab EX Intro Ch 5 (all) EX Prelab
4/2 Dehydration of an Alcohol DH Lab DH Intro Ch 10.3 DH Prelab
4/9-16 Hydrobromination of an Alkene

Take home NMR

Lab Notebooks collected

 HB Lab HB Intro Ch. 10.4 HB Prelab
4/23 Take Home NMR Project Due        
 
 

SOURCES OF INFORMATION

This is a short list of where you may find the information required for this course.  These are references where you might find densities, boiling points etc. for this lab:

1) Aldrich Chemical Catalog:This has the advantage of having many compounds in it, and listing them in alphabetical order.Watch out for grades of chemicals (Tech. 90% or ACS reagent grade 99.998%), and deuteration – addition of one or more deuterium atoms to replace hydrogen.The latter appears as, for example, “acetone-d 6”, or “ethyl acetate – d 3”.We will usually not use technical grade chemicals, and we never use isotopically substituted ones.

2) The Merck Index: Less comprehensive that Aldrich.Limited to chemicals that are biomedical in use.However, it is very readable.

3) The CRC Handbook of Physics and Chemistry (as well as other CRC books): This is an exhaustive compilation of organic compounds.  However, it helps a lot if you have a good grasp of organic nomenclature.For example, bromobenzene is “benzene, bromo”; and “n-butyl acetate” is “Acetic acid, n-butyl ester”.

4) Beilstein, the Dictionary of Chemistry, the Dictionary of Organic Compounds, and others are useful to some, but to me are either too hard to use, or incomplete.The ACS index is just as good and hard to use.

5) “On Line Sources” Yes, they are out there.But be specific on your URL citations, and be sure it is a reliable source.