COURSE DESCRIPTION

Introduces fundamentals chemistry of carbon compounds, including structures, physical properties, synthesis, and typical reactions. Emphasizes reaction mechanisms. Lecture 3 hours per week

GENERAL COURSE PURPOSE

A sequence of course designed to introduce the student to the chemistry of carbon compounds. It covers some of the historical aspects of organic chemistry as well as the relationships with industrial synthesis. Biochemistry as well as polymer chemistry is included. It covers the wide variety of synthesis methods and chemical group reactions.

ENTRY LEVEL COMPETENCY

One year of college chemistry or the equivalent or permission of the instructor.

COURSE OBJECTIVES

As a result of the learning experiences provided in this course, the student should be able to:

1. Apply bonding concepts, molecular architecture, and isomerism (structural, conformational, stereo) to the general aspects of organic structures
2. Use acid-base theory, electronic effects, and steric effects to correlate chemical reactivity and molecular structure
3. Identify oxidation, reduction, addition, substitution, elimination, rearrangement and cyclization reactions in the various organic reaction processes and mechanisms
4. Use activation parameters and thermodynamic parameters for first and second order reaction kinetics (including the use of reaction diagrams)
5. Give detailed consideration to specific classes of organic compounds and their types of reactions (such as alkanes, alkenes, alkynes, cycloalkanes, alkyl halides, and alcohols)
6. Complete challenging sequence syntheses of the specific classes of compounds included in #5 above
7. Give to IUPAC and common names of the classes of compounds given in #5 above as well as be able to determine the optical configurations of stereochemical compounds using the R,S convention, and give proper name to the geometric isomers using the E,Z convention

1. The atomic and hybrid orbitals of the carbon, oxygen, and nitrogen atoms. Molecular shapes resulting from the different hybrid patters. Resonance structures, Lewis structures, and isomerism of organic compounds.
2. Nomenclature, structures and conformations, physical properties, methods of preparation and reactions of the alkanes and cycloalkanes.
3. Acid-base theory (Arrhenius, Bronsted-Lowry, Lewis), thermodynamics and kinetics as related to organic reactions.
4. Mechanisms of the halogenation of methane and higher order alkanes.
5. Nomenclature, structures, physical properties, methods of preparation, and reactions of the alkyl halide compounds (emphasis on the Sn2, Sn1, E2, and E1 reactions with companison of substitution vs. Elimination).
6. Nomenclature (cis-trans and E,Z), structures (cis-trans isomerism), physical properties, methods of preparation and reactions of the alkenes (including electrophilic addition to the C=C bond by symmetrical molecules [H2, X2], and unsymmetrical modecules [HX {HBr in peroxide included}, H2O, HCN, HOC1, H2SO4, Hg (Oac)2, BH3], epoxidation reactions, hydroxylation reactions; oxidative cleavage reactions; dimerization reactions; and polymerization reactions). Stability of cis and trans alkenes.
7. Stereochemical nomenclature, terminology, Fischer projections, stereochemical reactions, and resolution of enantiomers.
8. Nomenclature, structures, physical properties, methods of preparation, and reactions of alcohols (including oxidation, reduction, substitution reactions, dehydration, acylation, salt and ether formation).
9. Nomenclature, structures, physical properties, methods of preparation, and reactions of the ethers and epoxides.
10. Nomenclature, structures, physical properties, methods of preparation, and reactions of the alkynes.

A. Muscle and connective tissue proteins

B. Experimental methods

C. Photosynthesis

D. Immunochemistry

E. Complex carbohydrates and glycoproteins

F. Neurochemistry

Revised 6/98