Material Safety Data
Sheet
1-Propanol 99+%
ACC# 19780
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Section 1 - Chemical Product and Company
Identification |
MSDS Name: 1-Propanol 99+%
Catalog Numbers: AC149480200, S80148, S80148-1, A414-1,
A414-20, A414-4, A414-500, A414S-4, BP1130-500
Synonyms: Propyl
Alcohol; n-Propyl Alcohol; n-Propanol; 1-Hydroxy Propane; Ethyl Carbinol.
Company Identification:
Fisher Scientific
1
Reagent Lane
Fair Lawn, NJ
07410
For information, call: 201-796-7100
Emergency
Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
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Section 2 -
Composition, Information on Ingredients |
| CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
| 71-23-8 |
n-Propyl alcohol |
>99 |
200-746-9 |
Hazard
Symbols: XI F
Risk Phrases: 11 41 67
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Section 3 - Hazards
Identification |
EMERGENCY OVERVIEW
Appearance: clear, colorless liquid. Flash Point: 15 deg C.
Warning! May cause eye and skin irritation. May cause
dermatitis. May cause central nervous system depression. May be harmful if
swallowed. Hygroscopic. Flammable liquid and
vapor. May cause respiratory tract irritation.
Target Organs:
Central nervous system, liver.
Potential Health
Effects
Eye: May
cause moderate eye irritation. May result in corneal injury.
Skin: May cause moderate skin irritation. Prolonged and/or
repeated contact may cause defatting of the skin and dermatitis.
Ingestion: May cause gastrointestinal irritation with
nausea, vomiting and diarrhea. May cause central nervous system depression,
characterized by excitement, followed by headache, dizziness, drowsiness, and
nausea. Advanced stages may cause collapse, unconsciousness, coma and possible
death due to respiratory failure.
Inhalation: Inhalation of
vapor may cause respiratory tract irritation. May cause effects similar to those
described for ingestion.
Chronic: Prolonged or repeated
skin contact may cause defatting and dermatitis. Chronic exposure may cause
liver damage.
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Section 4 - First Aid
Measures |
Eyes: Immediately flush eyes with plenty of water
for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get
medical aid.
Skin: Get medical aid. Flush skin with plenty
of soap and water for at least 15 minutes while removing contaminated clothing
and shoes.
Ingestion: Do NOT induce vomiting. If victim is
conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by
mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure to fresh air immediately.
If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Get medical aid.
Notes to Physician: Treat
symptomatically and supportively.
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Section 5 - Fire
Fighting Measures |
General
Information: Containers can build up pressure if exposed to heat and/or
fire. As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Combustion generates toxic fumes. During a fire, irritating and highly toxic
gases may be generated by thermal decomposition or combustion. Flammable Liquid.
Can release vapors that form explosive mixtures at temperatures above the
flashpoint. Vapors may be heavier than air. They can spread along the ground and
collect in low or confined areas.
Extinguishing Media: Use
water spray to cool fire-exposed containers. Use dry chemical, carbon dioxide,
or alcohol-resistant foam. Do NOT use straight streams of water.
Flash
Point: 15 deg C ( 59.00 deg F)
Autoignition Temperature: 405 deg
C ( 761.00 deg F)
Explosion Limits, Lower:2.2 vol %
Upper:
13.7 vol %
NFPA Rating: (estimated) Health: 1;
Flammability: 3; Instability: 0
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Section 6 -
Accidental Release Measures |
General
Information: Use proper personal protective equipment as indicated in
Section 8.
Spills/Leaks: Absorb spill with inert material
(e.g. vermiculite, sand or earth), then place in suitable container. Avoid
runoff into storm sewers and ditches which lead to waterways. Clean up spills
immediately, observing precautions in the Protective Equipment section. Use
water spray to disperse the gas/vapor. Remove all sources of ignition. Provide
ventilation.
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Section 7 - Handling
and Storage |
Handling: Wash thoroughly after handling. Remove
contaminated clothing and wash before reuse. Use with adequate ventilation. Use
spark-proof tools and explosion proof equipment. Empty containers retain product
residue, (liquid and/or vapor), and can be dangerous. Do not get on skin or in
eyes. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder,
drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Do not
store near combustible materials. Store in a cool, dry place. Store in a tightly
closed container. Keep from contact with oxidizing materials. Flammables-area.
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Section 8 - Exposure
Controls, Personal Protection |
Engineering
Controls: Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the permissible
exposure limits.
Exposure Limits
| Chemical Name |
ACGIH |
NIOSH |
OSHA -
Final PELs |
| n-Propyl alcohol |
200 ppm TWA; 250 ppm STEL; (skin) - potential for
cutaneous absorption |
200 ppm TWA; 500 mg/m3 TWA 800 ppm IDLH |
200 ppm TWA; 500 mg/m3
TWA |
OSHA Vacated PELs: n-Propyl
alcohol: 200 ppm TWA; 500 mg/m3 TWA; 250 ppm STEL; 625 mg/m3 STEL
Personal Protective Equipment
Eyes:
Wear chemical goggles.
Skin: Wear appropriate protective
gloves to prevent skin exposure.
Clothing: Wear appropriate
protective clothing to minimize contact with skin.
Respirators: A
respiratory protection program that meets OSHA's 29 CFR §1910.134 and ANSI Z88.2
requirements or European Standard EN 149 must be followed whenever workplace
conditions warrant a respirator's use.
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Section 9 - Physical
and Chemical Properties |
Physical State:
Liquid
Appearance: clear, colorless
Odor: alcohol-like
pH: Not available.
Vapor Pressure: 14.3 mm Hg @ 20
Vapor Density: 2.1 (Air=1)
Evaporation Rate:1.3 (butyl
acetate=1)
Viscosity: 2.2 mPas 20 deg C
Boiling Point: 97
deg C @ 760mm Hg
Freezing/Melting Point:-127 deg C
Decomposition Temperature:Not available.
Solubility:
Miscible.
Specific Gravity/Density:.8040g/cm3
Molecular
Formula:C3H8O
Molecular Weight:60.10
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Section 10 -
Stability and Reactivity |
Chemical
Stability: Stable under normal temperatures and pressures.
Conditions
to Avoid: Incompatible materials, ignition sources.
Incompatibilities
with Other Materials: Acid chlorides, acid anhydrides, oxidizing agents,
potassium tert-butoxide.
Hazardous Decomposition Products: Carbon
monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.
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Section 11 -
Toxicological Information |
RTECS#:
CAS# 71-23-8: UH8225000
LD50/LC50:
CAS#
71-23-8:
Draize test, rabbit, eye: 20 mg/24H Moderate;
Inhalation, mouse:
LC50 = 48 gm/m3;
Oral, mouse: LD50 = 6800 mg/kg;
Oral, rabbit: LD50 = 2825
mg/kg;
Oral, rat: LD50 = 1870 mg/kg;
Skin, rabbit: LD50 = 5040
mg/kg;
Carcinogenicity:
CAS# 71-23-8: Not listed by ACGIH,
IARC, NIOSH, NTP, or OSHA.
Epidemiology: Oral rat TDLo = 50 gm/kg/81
weeks. 1-Propanol caused liver t umors and leukemia according to RTECs criteria.
Teratogenicity: No information available.
Reproductive
Effects: An exposure of 7000 ppm/7 hours caused a reduction in fertility in
male rats and caused fetotoxic effects. A dose of 10000 ppm/7 hours caused
musculoskeletal abnormalities and post-implantation mortality.
Neurotoxicity: No information available.
Mutagenicity: No
information available.
Other Studies: See actual entry in RTECS for
complete information.
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Section 12 -
Ecological Information |
Ecotoxicity: No
data available. No information available.
Environmental: Expected to
rapidly volatilize.
Physical: No information available.
Other: No information available.
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Section 13 - Disposal
Considerations |
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
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Section 14 -
Transport Information |
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US
DOT |
IATA |
RID/ADR |
IMO |
Canada
TDG |
| Shipping Name: |
N-PROPANOL |
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No information available. |
| Hazard Class: |
3 |
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| UN Number: |
UN1274 |
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| Packing Group: |
II |
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Section 15 -
Regulatory Information |
US
FEDERAL
TSCA
CAS# 71-23-8 is listed on the TSCA
inventory.
Health & Safety Reporting List
None of the
chemicals are on the Health & Safety Reporting List.
Chemical Test
Rules
None of the chemicals in this product are under a Chemical Test
Rule.
Section 12b
None of the chemicals are listed under TSCA
Section 12b.
TSCA Significant New Use Rule
None of the chemicals
in this material have a SNUR under TSCA.
SARA
Section 302
(RQ)
None of the chemicals in this material have an RQ.
Section
302 (TPQ)
None of the chemicals in this product have a TPQ.
SARA
Codes
CAS # 71-23-8: acute, flammable.
Section 313
No
chemicals are reportable under Section 313.
Clean Air Act:
This
material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2
Ozone depletors.
Clean Water Act:
None of the chemicals in this
product are listed as Hazardous Substances under the CWA. None of the chemicals
in this product are listed as Priority Pollutants under the CWA. None of the
chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly
hazardous by OSHA.
STATE
CAS# 71-23-8 can be found on the
following state right to know lists: California, New Jersey, Florida,
Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk
Level: None of the chemicals in this product are listed.
European/International Regulations
European
Labeling in Accordance with EC Directives
Hazard Symbols:
XI F
Risk Phrases:
R 11 Highly flammable.
R 41 Risk of serious
damage to eyes.
R 67 Vapors may cause drowsiness and dizziness.
Safety Phrases:
S 16 Keep away from sources of ignition - No
smoking.
S 24 Avoid contact with skin.
S 26 In case of contact with
eyes, rinse immediately
with plenty of water and seek medical advice.
S
39 Wear eye/face protection.
S 7 Keep container tightly closed.
WGK (Water Danger/Protection)
CAS# 71-23-8: 1
Canada -
DSL/NDSL
CAS# 71-23-8 is listed on Canada's DSL List.
Canada -
WHMIS
This product has a WHMIS classification of B2, D2B.
Canadian
Ingredient Disclosure List
CAS# 71-23-8 is listed on the Canadian
Ingredient Disclosure List.
Exposure Limits
CAS# 71-23-8:
OEL-AUSTRALIA:TWA 200 ppm (500 mg/m3);STEL 250 ppm;Ski
n OEL-BELGIUM:TWA 200
ppm (492 mg/m3);STEL 250 ppm;Skin OEL-CZECHOSL
OVAKIA:TWA 500 mg/m3;STEL 1000
mg/m3 OEL-DENMARK:TWA 200 ppm (500 mg/
m3);Skin OEL-FINLAND:TWA 200 ppm (500
mg/m3);STEL 250 ppm;Skin OEL-F
RANCE:TWA 200 ppm (500 mg/m3) OEL-HUNGARY:TWA
100 mg/m3;STEL 200 mg/m
3 OEL-POLAND:TWA 200 mg/m3 OEL-RUSSIA:STEL 10 mg/m3
OEL-SWEDEN:TWA
150 ppm (350 mg/m3);STEL 250 ppm (all isomers)
OEL-SWITZERLAND:TWA 20
0 ppm (500 mg/m3);Skin JAN9 OEL-TURKEY:TWA 200 ppm
(500 mg/m3) OEL-U
NITED KINGDOM:TWA 200 ppm (500 mg/m3);STEL 250 ppm;Skin OEL
IN BULGAR
IA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND,
SINGA
PORE, VIETNAM check ACGI TLV
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Section 16 -
Additional Information |
MSDS Creation Date:
12/12/1997
Revision #6 Date: 3/14/2001
The information above is
believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability
resulting from its use. Users should make their own investigations to determine
the suitability of the information for their particular purposes. In no event
shall Fisher be liable for any claims, losses, or damages of any third party or
for lost profits or any special, indirect, incidental, consequential or
exemplary damages, howsoever arising, even if Fisher has been advised of the
possibility of such damages.