Material Safety Data Sheet
1-Propanol 99+%

ACC# 19780
Section 1 - Chemical Product and Company Identification

MSDS Name: 1-Propanol 99+%
Catalog Numbers: AC149480200, S80148, S80148-1, A414-1, A414-20, A414-4, A414-500, A414S-4, BP1130-500
Synonyms:
Propyl Alcohol; n-Propyl Alcohol; n-Propanol; 1-Hydroxy Propane; Ethyl Carbinol.
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
71-23-8 n-Propyl alcohol >99 200-746-9

Hazard Symbols:
XI F
Risk Phrases:
11 41 67

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: clear, colorless liquid. Flash Point: 15 deg C. Warning! May cause eye and skin irritation. May cause dermatitis. May cause central nervous system depression. May be harmful if swallowed. Hygroscopic. Flammable liquid and vapor. May cause respiratory tract irritation.
Target Organs: Central nervous system, liver.


Potential Health Effects
Eye: May cause moderate eye irritation. May result in corneal injury.
Skin: May cause moderate skin irritation. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure.
Inhalation: Inhalation of vapor may cause respiratory tract irritation. May cause effects similar to those described for ingestion.
Chronic: Prolonged or repeated skin contact may cause defatting and dermatitis. Chronic exposure may cause liver damage.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: Containers can build up pressure if exposed to heat and/or fire. As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustion generates toxic fumes. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Flammable Liquid. Can release vapors that form explosive mixtures at temperatures above the flashpoint. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas.
Extinguishing Media: Use water spray to cool fire-exposed containers. Use dry chemical, carbon dioxide, or alcohol-resistant foam. Do NOT use straight streams of water.
Flash Point: 15 deg C ( 59.00 deg F)
Autoignition Temperature: 405 deg C ( 761.00 deg F)
Explosion Limits, Lower:2.2 vol %
Upper: 13.7 vol %
NFPA Rating: (estimated) Health: 1; Flammability: 3; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, observing precautions in the Protective Equipment section. Use water spray to disperse the gas/vapor. Remove all sources of ignition. Provide ventilation.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Use spark-proof tools and explosion proof equipment. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not get on skin or in eyes. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Do not store near combustible materials. Store in a cool, dry place. Store in a tightly closed container. Keep from contact with oxidizing materials. Flammables-area.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
n-Propyl alcohol 200 ppm TWA; 250 ppm STEL; (skin) - potential for cutaneous absorption 200 ppm TWA; 500 mg/m3 TWA 800 ppm IDLH 200 ppm TWA; 500 mg/m3 TWA

OSHA Vacated PELs: n-Propyl alcohol: 200 ppm TWA; 500 mg/m3 TWA; 250 ppm STEL; 625 mg/m3 STEL
Personal Protective Equipment
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: A respiratory protection program that meets OSHA's 29 CFR §1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear, colorless
Odor: alcohol-like
pH: Not available.
Vapor Pressure: 14.3 mm Hg @ 20
Vapor Density: 2.1 (Air=1)
Evaporation Rate:1.3 (butyl acetate=1)
Viscosity: 2.2 mPas 20 deg C
Boiling Point: 97 deg C @ 760mm Hg
Freezing/Melting Point:-127 deg C
Decomposition Temperature:Not available.
Solubility: Miscible.
Specific Gravity/Density:.8040g/cm3
Molecular Formula:C3H8O
Molecular Weight:60.10

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Incompatible materials, ignition sources.
Incompatibilities with Other Materials: Acid chlorides, acid anhydrides, oxidizing agents, potassium tert-butoxide.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - Toxicological Information


RTECS#:
CAS# 71-23-8: UH8225000
LD50/LC50:
CAS# 71-23-8:
Draize test, rabbit, eye: 20 mg/24H Moderate;
Inhalation, mouse: LC50 = 48 gm/m3;
Oral, mouse: LD50 = 6800 mg/kg;
Oral, rabbit: LD50 = 2825 mg/kg;
Oral, rat: LD50 = 1870 mg/kg;
Skin, rabbit: LD50 = 5040 mg/kg;
Carcinogenicity:
CAS# 71-23-8: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: Oral rat TDLo = 50 gm/kg/81 weeks. 1-Propanol caused liver t umors and leukemia according to RTECs criteria.
Teratogenicity: No information available.
Reproductive Effects: An exposure of 7000 ppm/7 hours caused a reduction in fertility in male rats and caused fetotoxic effects. A dose of 10000 ppm/7 hours caused musculoskeletal abnormalities and post-implantation mortality.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: See actual entry in RTECS for complete information.

Section 12 - Ecological Information


Ecotoxicity: No data available. No information available.
Environmental: Expected to rapidly volatilize.
Physical: No information available.
Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT IATA RID/ADR IMO Canada TDG
Shipping Name: N-PROPANOL No information available.
Hazard Class: 3
UN Number: UN1274
Packing Group: II

Section 15 - Regulatory Information

US FEDERAL

TSCA
CAS# 71-23-8 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA

Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 71-23-8: acute, flammable.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 71-23-8 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
XI F
Risk Phrases:

R 11 Highly flammable.
R 41 Risk of serious damage to eyes.
R 67 Vapors may cause drowsiness and dizziness.

Safety Phrases:

S 16 Keep away from sources of ignition - No
smoking.
S 24 Avoid contact with skin.
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 39 Wear eye/face protection.
S 7 Keep container tightly closed.

WGK (Water Danger/Protection)

CAS# 71-23-8: 1
Canada - DSL/NDSL
CAS# 71-23-8 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B2, D2B.
Canadian Ingredient Disclosure List
CAS# 71-23-8 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 71-23-8: OEL-AUSTRALIA:TWA 200 ppm (500 mg/m3);STEL 250 ppm;Ski
n OEL-BELGIUM:TWA 200 ppm (492 mg/m3);STEL 250 ppm;Skin OEL-CZECHOSL
OVAKIA:TWA 500 mg/m3;STEL 1000 mg/m3 OEL-DENMARK:TWA 200 ppm (500 mg/
m3);Skin OEL-FINLAND:TWA 200 ppm (500 mg/m3);STEL 250 ppm;Skin OEL-F
RANCE:TWA 200 ppm (500 mg/m3) OEL-HUNGARY:TWA 100 mg/m3;STEL 200 mg/m
3 OEL-POLAND:TWA 200 mg/m3 OEL-RUSSIA:STEL 10 mg/m3 OEL-SWEDEN:TWA
150 ppm (350 mg/m3);STEL 250 ppm (all isomers) OEL-SWITZERLAND:TWA 20
0 ppm (500 mg/m3);Skin JAN9 OEL-TURKEY:TWA 200 ppm (500 mg/m3) OEL-U
NITED KINGDOM:TWA 200 ppm (500 mg/m3);STEL 250 ppm;Skin OEL IN BULGAR
IA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGA
PORE, VIETNAM check ACGI TLV

Section 16 - Additional Information

MSDS Creation Date: 12/12/1997
Revision #6 Date: 3/14/2001

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.