NVCC COLLEGE-WIDE COURSE CONTENT SUMMARY
BIO 146 - HUMAN HEREDITY (3 CR.)
Revised 1/97
 

COURSE DESCRIPTION

Surveys basic principles of classical and molecular genetics as applied to humans. Lecture 3 hours per week.

GENERAL COURSE PURPOSE

This course is designed for non-biology majors and serves as an elective. The course is intended for both the college student and members of the community who are interested in understanding the basic principles of genetics as it applies to humans.

ENTRY LEVEL COMPETENCIES

The student should be able to read, write, and communicate orally in English.

COURSE OBJECTIVES

Upon completion of this course, the student should be able to:

A. recognize the basic structure of a cell and describe the function of its component parts
B. identify the role of DNA and RNA in cell functioning
C. describe the process of cell division -- mitosis and meiosis
D. compare and contrast spermatogenesis with oogenesis and explain the implications of the differences
E. describe the male and female reproductive process
F. trace human embryological development
G. describe the chromosomal basis of inheritance and relate this to human chromosomal abnormalities
H. identify basic Mendelian principles as applied to human inheritance
I. construct and interpret basic pedigree data
J. describe the inheritance of the ABO blood group system, the Rh blood group system and the HLA complex
K. describe the mechanism of sex determination and sex linkage
L. describe the molecular concept of the "gene" including biochemical action and regulation
M. describe how genetic mutations occur and their effect on gene regulation and expression
N. use inborn errors of metabolism as a model to study gene action
O. discuss the concepts of population genetics and quantitative inheritance
P. explain the role of genetic counseling
Q. evaluate the impact on society of the application of new genetic techniques to the fields of human reproduction, gene technology and treatment of disease
MAJOR TOPICS TO BE COVERED A. History of Genetics (brief)
B. The Cell
C. Cell Division - Mitosis
D. Meiosis
E. Human Reproduction
F. Human Chromosomes
G. Sex-determination
H. Chromosome Abnormalities
I. Human Development
J. Mendelian Principles
K. Pedigrees
L. Blood Factor Genetics - ABO, Rh, HLA
M. Sex-linkage
N. Biochemical Nature of the Gene
O. Protein Synthesis
P. Gene Regulation
Q. Mutations
R. Inborn Errors of Metabolism
S. Population Genetics
T. Quantitative Inheritance
U. Genetic Counseling
V. New Genetic Techniques and Applications
OPTIONAL TOPICS

The instructor may present any of the major topics in greater depth, such as effects of environmental agents on human development, immunogenetics, gene technology, etc.


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